The Guidelines have been revised to focus on CCS instead of stable CAD in order to emphasize the fact that the
clinical presentations of CAD can be categorized as either acute coronary syndromes (ACS) or CCS (1). Six
clinical scenarios most frequently encountered in patients have been identified: from naive and asymptomatic
patients to symptomatic patients (angor/dyspnea) presenting after an ACS. The pretest probability (PTP) of
CAD based on age, gender and nature of symptoms have undergone major revisions and the concept « Clinical
likelihood of CAD » has been introduced that utilizes also various risk factors of CAD as PTP modifiers (Table &
Figure). New recommendations can be divided in three categories: